Three AI reviewers screen every abstract
Claude, GPT-4o, and Gemini independently vote include / exclude on each title and abstract. Unanimous decisions auto-route. Disagreements surface for human review with Cohen's κ inter-rater reliability so you know exactly where to focus.
- includeFaricimab vs Aflibercept in Treatment-Naïve Neovascular AMD: 12-Month Results of the TENAYA TrialKhanani A.M., Guymer R.H., et al. · Ophthalmology (2026)Cinclude95%Ginclude92%Gminclude90%
- excludeReal-World Six-Month Outcomes After Switching from Aflibercept 2 mg to 8 mgKindo H., Hosokawa M., et al. · Japanese Journal of Ophthalmology (2026)Cexclude95%Gexclude90%Gmexclude95%
- includeA Phase III Randomized Trial Comparing ZRC-3285 vs Eylea® in Wet AMDBansal M., Singh P., et al. · Ophthalmology and Therapy (2026)Cinclude95%Ginclude95%Gminclude95%
- excludeCost-Utility Analysis of Faricimab vs Aflibercept in nAMDBaljoon A., Diaby V., et al. · PharmacoEconomics — Open (2026)Cexclude90%Gexclude95%Gmexclude95%
- Human reviewTwelve-Month Outcomes of Aflibercept 8 mg in Treatment-Naïve Diabetic Macular EdemaSpindler J., Artemiev D., et al. · Ophthalmology Science (2026)Cinclude80%Guncertain60%Gmexclude70%
Sample data from a real ophthalmology meta-analysis. Live screening processes thousands of records in minutes.
Everything a systematic review demands.
A complete evidence-synthesis workflow from PICO to publication, in one platform.
Dual-pass AI screening
Claude AI screens every abstract twice and flags borderline cases. Cohen's κ inter-rater reliability scores tell you exactly where to focus.
Meta-analysis engine
Random- and fixed-effects models with forest plots, funnel plots, and I² heterogeneity — computed in-platform, exportable to your manuscript.
Multi-database search
PubMed, Embase, Cochrane, and ClinicalTrials.gov queried simultaneously with one PICO.
Vector deduplication
Fuzzy matching plus embedding similarity eliminate duplicates before screening.
Risk of bias
RoB2 and ROBINS-I frameworks with auto-generated GRADE evidence tables.
Protocol generation
PRISMA-P compliant protocols with eligibility criteria and PROSPERO-ready output.
Full-text review
Structured screening with exclusion reasons mapped to PRISMA flow categories.
PRISMA 2020 reporting
Auto-generated PRISMA flow diagrams and full reports — exportable as JSON, CSV, RIS, BibTeX, or SVG.
From question to evidence in five steps.
A guided workflow that matches how systematic reviews are actually conducted.
- 01
Define your PICO
Set population, intervention, comparator, and outcome with guided templates.
- 02
Search & import
Query multiple databases. We deduplicate and import in seconds.
- 03
AI screens abstracts
Claude processes thousands of abstracts. You review only the borderlines.
- 04
Extract & assess
Structured data extraction and automated risk of bias assessment.
- 05
Meta-analyse & report
Statistical synthesis, visualisations, and PRISMA-compliant export.